Talo Systems is an early-stage therapeutics focused company based in Singapore. Led by a team of experienced drug development and computer scientists, we are a multi-disciplinary team of software developers, artificial intelligence engineers, bioinformaticians, chemists, and more. Together, our team is working to change the way that therapeutics are developed — at all phases of pre-clinical research and development.
A successful candidate will have a good understanding of medicinal and synthetic chemistry principles and drug discovery, and possess the necessary problem solving and communication skills to collaborate in a multi-discipline team setting. The position requires an individual with a strong work ethic who is highly motivated and excited to work in a collaborative environment.
Responsibilities:
- Design of small molecule drugs targeting disease relevant pathways
- Responsible for route selection, design, and multi-step synthesis
- Apply Medicinal Chemistry knowledge and experience to assess molecule properties, SAR, and design new analogues to achieve clinical candidate profile
- Use and provide feedback on our proprietary in silico tools to guide drug design and development
- Keep up to date knowledge of novel chemistry literature and technology methodologies
- Must possess good scientific problem-solving ability
Requirements:
- Degree or Ph.D. in Organic Chemistry
- Demonstrated record of productivity in Medicinal or synthetic chemistry research as evidenced by publications and/or patents
- Medicinal Chemistry knowledge and experience – 3 years minimum
- Excellent scientific problem-solving skills with the ability to perform research independently
- Strong interpersonal and communication skills (both written and verbal)
- Ability to work collaboratively in a team
- Strong work ethic with good time management skills
- A strong desire to contribute in a collaborative fashion with an ability to present his/her point of view and influence the project